Abstract Library
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#3320 TGF-β increase caspase activation and migration in typical bronchial carcinoids
Introduction: Typical bronchial carcinoids (TBC) are well-differentiated neuroendocrine neoplasms (NEN) whose management can still be very challenging due to reduced sensitivity to therapy. Previous studies have reported TGF-β’s ability to activate mTOR pathway and induce epithelial to mesenchymal transition (EMT). Moreover, preliminary results show an overexpression of TGF-β signalling and caspase activation in TBC.
Conference: 18th Annual ENETS Concerence (2021)
Presenting Author: Gagliardi I
Authors: Borges de Souza P, Gagliardi I, Martelli M, Zatelli M,
Keywords: bronchial carcinoid, TGF-β signalling, mTOR, EMT,
Introduction: Neuroendocrine carcinoma (NEC) is an extremely rare subtype of endometrial cancer which is usually seen among perimenopausal or postmenopausal women. It runs an aggressive course and posts a clinical challenge due to limited treatment options available.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Cruz M
Keywords: neuroendocrine carcinoma, endometrium,
Introduction: Management of NET patients often involves a multidisciplinary approach,requiring collaboration between referring oncologists,surgeons,endocrinologists locally and NET specialty centers (NSC).
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Yelamanchili R
Authors: Radhika Y, Chan D, Thawer A, Lo D, Singh S,
Keywords: Shared care, NET, Local Medical Oncologists, NET specialty centers,
Introduction: The efficacy of somatostatin analogs (SSAs) were clearly established trough pivotal trials as first‐line agents for neuroendocrine tumors (NETs), but their use in clinical practice is largely unknown.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Ameziane N, Behourah Z, Aida M, Ahed Messaoud M, Bousahba A,
Keywords: GEP-NET, Somatostatin analogs, anti proliferative action, anti secretory action, Management real world practice,
Introduction: Gastroenteropancreatic neuroendocrine tumours (GEP NET) can adversely affect nutritional status. Cross-sectional studies report up to 25% of GEP NET patients are malnourished and dietary change may be prevalent. Nevertheless, clinical guidelines lack advice on nutrition management.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Laing E
Authors: Laing E, Kiss N, Michael M, Krishnasamy M, Gough K,
Keywords: neuroendocrine, nutrition, malnutrition, weight change, symptoms,